{"product_id":"premier-joint-disc","title":"Joint \u0026 Disc, Premier","description":"\u003cstyle\u003e#html-body [data-pb-style=F4MA1DE]{justify-content:flex-start;display:flex;flex-direction:column;background-position:left top;background-size:cover;background-repeat:no-repeat;background-attachment:scroll;border-style:none;border-width:1px;border-radius:0;margin:0 0 10px;padding:10px}#html-body [data-pb-style=LXNNBNG]{border-style:none;border-width:1px;border-radius:0;margin:0;padding:0}\u003c\/style\u003e\u003cdiv data-content-type=\"row\" data-appearance=\"contained\" data-element=\"main\"\u003e\u003cdiv data-enable-parallax=\"0\" data-parallax-speed=\"0.5\" data-background-images=\"{}\" data-background-type=\"image\" data-video-loop=\"true\" data-video-play-only-visible=\"true\" data-video-lazy-load=\"true\" data-video-fallback-src=\"\" data-element=\"inner\" data-pb-style=\"F4MA1DE\"\u003e\u003cdiv data-content-type=\"text\" data-appearance=\"default\" data-element=\"main\" data-pb-style=\"LXNNBNG\"\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cstrong\u003e\u003ca tabindex=\"0\" href=\"https:\/\/prlabs.com\/media\/wysiwyg\/prlabs\/Technical_Bulletin\/Disc-and-Joint_Booklet.pdf\" target=\"_blank\" rel=\"noopener\"\u003eTechnical Bulletin\u003c\/a\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003ePremier Joint \u0026amp; Disc\u003c\/strong\u003e is a premier nature-based botanical formula, clinically formulated to support a healthy inflammatory response and minor pain relief from normal day to day joint wear and tear,* specific to:\u003c\/p\u003e\r\n\u003cul\u003e\r\n\u003cli\u003eJoint mobility*\u003c\/li\u003e\r\n\u003cli\u003eDisc health*\u003c\/li\u003e\r\n\u003cli\u003eHealthy cartilage*\u003c\/li\u003e\r\n\u003cli\u003eSports recovery \/ muscle function*\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cp\u003e\u003cstrong\u003ePremier Joint \u0026amp; Disc\u003c\/strong\u003e is scientifically formulated to deliver an aggressive panel of clinically reviewed ingredients which contain powerful phytochemical compounds designed to directly promote a healthy inflammatory response by targeting key chemical signaling pathways that have the capacity to modulate pro-inflammatory cytokines and proteins associated with minor pain from everyday activities.* \u003c\/p\u003e\r\n\u003cp\u003e \u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003eTriple Strength Formula\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003eThis triple strength formula is tailored with three clinically reviewed ingredients designed to provide long-term support of the joints, discs and musculoskeletal systems of the body.*  Leading the list of this trifecta is the distinguished, centuries-old \u003cem\u003eAndrographis paniculata\u003c\/em\u003e, patented as ParActin®. This revered botanical continues to be regarded by health professionals worldwide as one of nature’s superstars providing reliable results to their clients who need immediate joint support.* \u003c\/p\u003e\r\n\u003cp\u003eComplementing this notable ingredient is the well-researched White Willow (bark) Extract, which provides the highly effective compound, salicin.  Lastly, anchoring the trio, is Sodium Hyaluronate which is well known for its active constituent, hyaluronic acid.\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003ePremier Joint \u0026amp; Disc\u003c\/strong\u003e is a comprehensive formula offering an elegant lineup of advanced, full spectrum botanical compounds that promote healthy joints, discs and connective tissue function.*\u003c\/p\u003e\r\n\u003cp\u003e \u003c\/p\u003e\r\n\u003cp style=\"text-align: center;\"\u003e\u003cspan style=\"font-size: 16px;\"\u003e\u003cstrong\u003eAndrographis Paniculata\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003eWhat is it?\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eAndrographis paniculata\u003c\/em\u003e\u003c\/strong\u003e\u003cstrong\u003e,\u003c\/strong\u003e an annual herbaceous plant in the family Acanthaceae, is one of the most commonly used medicinal plants in the traditional systems of Traditional Chinese and Ayurvedic medicine.* It continues to be widely cultivated in India, China, and Southeastern Asia.  Known as the “King of Bitters,” its bioactive components called andrographolides have been extensively tested and have demonstrated their ability to promote modulatory activity at multiple points in the chemical signaling pathway of the inflammatory response systems of the body.*\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003eHow Does it work?\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003ePRL selected ParActin®, a nature-sourced, patented extract of \u003cem\u003eAndrographis paniculata\u003c\/em\u003e, as a primary ingredient in our formulation, \u003cstrong\u003ePremier Joint \u0026amp; Disc\u003c\/strong\u003e.  ParActin® is the result of over 20 years of research and development including more than 30 studies of in vitro \/ in vivo animal models and human clinical trials.  This extract’s diterpenoid profile is standardized to clinically established levels that promote a healthy inflammatory response due to the targeting of key chemical signaling pathways which support healthy NF-kB levels and activity, known as the master regulator of our inflammatory response systems.*\u003c\/p\u003e\r\n\u003cp\u003e \u003c\/p\u003e\r\n\u003cp style=\"text-align: center;\"\u003e\u003cspan style=\"font-size: 16px;\"\u003e\u003cstrong\u003eSalicin\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003eWhat is it?\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003eSalicin \u003c\/strong\u003eis a natural compound derived from the bark of the White Willow Tree. The use of White Willow Bark dates back to the early origins of medicine when Hippocrates first documented its efficacy in supporting the body during episodes of minor aches and pains.\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003eHow does it work?\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003eRecent science has found evidence that White Willow Bark’s primary phytochemical, Salicin, demonstrates a beneficial effect on both arachidonic acid-derived eicosanoids and cytokine compounds.* Randomized human trials have illustrated Salicin’s ability to influence the inflammatory response systems as a natural inhibitor of both the cyclooxygenase-2 (COX-2) and 5-lipoxygenase enzymes, beneficially modulating the activity of the protein complex \u003cem\u003enuclear factor-kappa B\u003c\/em\u003e (NF-kB), thereby regulating inflammatory cytokine production.*\u003c\/p\u003e\r\n\u003cp\u003e \u003c\/p\u003e\r\n\u003cp style=\"text-align: center;\"\u003e\u003cspan style=\"font-size: 16px;\"\u003e\u003cstrong\u003eHyaluronic Acid\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003eWhat is it?\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003eOptimal levels of synovial fluid in joint cavities is essential to maintaining healthy joints and mobility. Synovial fluid is the “viscous fluid” that supports the integrity of joints by shuttling in nutrients and keeping the cartilage hydrated and healthy.  Synovial fluid contains high levels of hyaluronic acid (HA) in its membrane to promote its fluid viscosity and is critical to preserving the normal cartilaginous matrix.* HA is a naturally occurring polymer found in all joints, discs, connective tissue, tendons, bones and cartilage (especially the hyaline cartilage, which covers the ends of bones to provide cushioning).* \u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003eHow does it work?\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003eHA is considered to be a glycosaminoglycan, composed of alternating units of n-acetyl-d-glucosamine and d-glucuronate.  This structure enables it to have the capacity to attract and retain large volumes of water in the extracellular matrix of tissues, various layers of the skin, and within the synovial fluid.  Ensuring optimal levels of hyaluronic acid is thus crucial to healthy joint function.*\u003c\/p\u003e\r\n\u003cp\u003eIn \u003cstrong\u003ePremier Joint \u0026amp; Disc\u003c\/strong\u003e, we use a stabilized form of hyaluronic acid called sodium hyaluronate which is more stable and less prone to oxidation. It is clearly the preferred form to support the health of joints and cartilage.*\u003c\/p\u003e\r\n\u003cp\u003e \u003c\/p\u003e\r\n\u003cp style=\"text-align: center;\"\u003e\u003cspan style=\"font-size: 16px;\"\u003e\u003cstrong\u003eTop Ten Premier Joint Support Products\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003e1. \u003cspan style=\"text-decoration: underline; color: #000000;\"\u003e\u003ca style=\"color: #000000; text-decoration: underline;\" tabindex=\"0\" href=\"https:\/\/prlabs.com\/premier-joint-disc.html\"\u003ePremier Joint \u0026amp; Disc\u003c\/a\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003eNature-sourced botanical formula, clinically formulated to support a healthy inflammatory response and minor pain relief specific to: ● Joint mobility ● Disc health ● Healthy cartilage ● Sports recovery \/ muscle function.*\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003e2.\u003cspan style=\"color: #000000;\"\u003e \u003cspan style=\"text-decoration: underline;\"\u003e\u003ca style=\"color: #000000; text-decoration: underline;\" tabindex=\"0\" href=\"https:\/\/prlabs.com\/inflammacidintm.html\"\u003eInflammacidin™\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003eWith 15 million PU of total protease activity, this formula is clinically designed to target a healthy inflammatory response without unwanted side effects.* Research demonstrates that high proteolytic activity acts as an essential modulator in supporting healthy inflammatory response, specific to the breakdown of proteins.\u003cem\u003e Thus, high proteolytic activity may promote healthy platelet function and also support joint comfort.\u003c\/em\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003e3. \u003cspan style=\"text-decoration: underline; color: #000000;\"\u003e\u003ca style=\"color: #000000; text-decoration: underline;\" tabindex=\"0\" href=\"https:\/\/prlabs.com\/epa-dha-marine.html\"\u003eEPA \/ DHA Marine Liquid\u003c\/a\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003eResearch studies have shown that omega-3 fatty acids are able to: 1) antagonize arachidonic acid-induced eicosanoid formation; 2) help generate resolvins and protectins to aid the body’s “cleanup” response to the arachidonic acid cascade; and 3) promote neurological health, cytokine balance and joint health.*\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003e4. \u003cspan style=\"text-decoration: underline;\"\u003e\u003ca tabindex=\"0\" href=\"https:\/\/prlabs.com\/tranquinol-trade.html\"\u003e\u003cspan style=\"color: #000000; text-decoration: underline;\"\u003eTranquinol\u003csup\u003e®\u003c\/sup\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003eThis formula supports overall body relaxation and mental tranquility by promoting a healthy neuromodulation response during times of stress. It helps counteract stress via the hypothalamus-pituitary-adrenal axis.*\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003e5. \u003cspan style=\"text-decoration: underline; color: #000000;\"\u003e\u003ca style=\"color: #000000; text-decoration: underline;\" tabindex=\"0\" href=\"https:\/\/prlabs.com\/glucosamine-premier.html\"\u003ePremier Glucosamine Sulfate\u003c\/a\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003eThis formula provides the premier form of glucosamine as glucosamine sulfate (shellfish-free), which promotes targeted joint, ligament and connective tissue support.*\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003e6. \u003cspan style=\"text-decoration: underline; color: #000000;\"\u003e\u003ca style=\"color: #000000; text-decoration: underline;\" tabindex=\"0\" href=\"https:\/\/prlabs.com\/vitamin-d3-k2.html\"\u003ePremier Vitamin D3+K2\u003c\/a\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003eAt a 5,000 IU of D3 and 180 mcg of K2 per capsule, this product contains an exclusive 100% vegan\/ vegetarian friendly formula with both vitamin D3 and K2 present in clinically established dosages that promote bone health as well as cardiovascular health.*\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003e7. \u003cspan style=\"text-decoration: underline; color: #000000;\"\u003e\u003ca style=\"color: #000000; text-decoration: underline;\" tabindex=\"0\" href=\"https:\/\/prlabs.com\/asta-complete-fx.html\"\u003eAstax\u003c\/a\u003eanthin Complex\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003eThis formula features algae-sourced astaxanthin which has the significant ability to quench ROS (reactive oxygen species) and free radicals (including the superoxide anion, hydrogen peroxide, singlet oxygen, etc.) in both the inner and outer layers of the cellular membrane -- unlike most other antioxidants which act on the inner membrane only (such as  vitamin E) or the outer membrane only (such as vitamin C).*\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003e8. \u003cspan style=\"text-decoration: underline; color: #000000;\"\u003e\u003ca style=\"color: #000000; text-decoration: underline;\" tabindex=\"0\" href=\"https:\/\/prlabs.com\/pqq-complex-with-coq10.html\"\u003ePQQ Complex\u003c\/a\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003eThis formula offers PQQ (pyrroloquinoline quinone), a unique B vitamin-like nutrient, which helps neutralize free radical stress and helps modulate neurotransmitter activity.\u003cem\u003e  It promotes the overall health of mitochondrial DNA and may help support healthy levels of nerve growth factor and supporting the functions of synaptic and intracellular neuronal responses.\u003c\/em\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003e9. \u003cspan style=\"text-decoration: underline; color: #000000;\"\u003e\u003ca style=\"color: #000000; text-decoration: underline;\" tabindex=\"0\" href=\"https:\/\/prlabs.com\/turmeric-32940d.html\"\u003ePremier Turmeric\u003c\/a\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003eThis product contains high quality, organic turmeric with a high concentration of active compounds known as curcuminoids, present as a naturally occurring component of turmeric. They possess significant antioxidant capabilities.*\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003e10.\u003cspan style=\"color: #000000;\"\u003e \u003cspan style=\"text-decoration: underline;\"\u003e\u003ca style=\"color: #000000; text-decoration: underline;\" tabindex=\"0\" href=\"https:\/\/prlabs.com\/complete-b-premier.html\"\u003ePremier Complete B Capsules\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003eThis product offers all 8 types of critical B vitamins that are all present in their fully activated, blood-circulating forms, including vitamin B6, which has been shown to directly support tendon health and nerve comfort.*\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/div\u003e\u003c\/div\u003e","brand":"Limitless Health Store","offers":[{"title":"Default Title","offer_id":47834234257634,"sku":"2363","price":37.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0796\/7657\/1874\/files\/2363_Joint_and_Disc_Bottle_1_eeb19d94-24c8-475a-8286-011d51cb8b10.png?v=1779944899","url":"https:\/\/shop.julieehealth.com\/products\/premier-joint-disc","provider":"Limitless Health Store","version":"1.0","type":"link"}